BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.8 nM/1.7 nM in cell-free assays, less potent to Met, Aurora A/B, TrkA/B and Ron, and shows little activity to Flt3, Lck, MK2, PKA, PKC etc. Phase 2.

　　BMS-754807

　　Molecular Weight (MW):461.49

　　Formula:C23H24FN9O

　　Solubility :DMSO