浩瀚色谱（山东）应用技术开发有限公司，《中guo药典》2010年版第三增补本中GC法测定甲醇量检查法中存在的问题。方法分别比较《中guo药典》2010年版一部附录ⅨT及第三增补本所载方法进行实验,并对结果进行分析比较。结果《中guo药典》2010年版第三增补本所载甲醇量测定方法在实际操作中存在顶空进样平衡时间及分流比设定不合理的问题。结论应延长平衡时间,增大分流比比例,以运用于实际检验工作。

　　编号:20231007007

　　型号:HQ填充柱

　　规格:2m*1/8，60-80目

　　使用温度:200°C

　　应用:药典甲醇测定

　　Haohan Chromatography (Shandong) Application Technology Development Co., Ltd., the third supplement to the 2010 edition of the Chinese Pharmacopoeia, discusses the problems in the GC method for determining methanol content. The methods were compared with the methods listed in Appendix IX T and the third supplement of the 2010 edition of the Chinese Pharmacopoeia, and the results were analyzed and compared. The method for determining methanol content in the third supplement of the 2010 edition of the "Zhongguo Pharmacopoeia" has problems with unreasonable headspace injection equilibrium time and split ratio settings in practical operation. The conclusion is that the balance time should be extended and the proportion of diversion ratio should be increased for practical inspection work.

　　No.: 20231007007

　　Model: HQ filled column

　　Specification: 2m * 1/8, 60-80 mesh

　　*High operating temperature: 200 ° C

　　Application: Pharmacopoeia Methanol Determination